Population pharmacokinetic modelling of febuxostat in healthy subjects and people with gout

AIMS: To investigate and characterise the pharmacokinetics of febuxostat and the effect of the covariates of renal function and body size descriptors on the pharmacokinetics of the drug. METHODS: Blood samples (n = 239) were collected using sparse and rich sampling strategies from healthy (n = 9) an...

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Detalles Bibliográficos
Autores principales: Kamel, Bishoy, Abuhelwa, Ahmad Y., Foster, David, Duong, Janna K., Graham, Garry G., Williams, Kenneth M., Pile, Kevin D., Day, Richard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796681/
https://www.ncbi.nlm.nih.gov/pubmed/35849446
http://dx.doi.org/10.1111/bcp.15462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796681/
https://www.ncbi.nlm.nih.gov/pubmed/35849446
http://dx.doi.org/10.1111/bcp.15462

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