Selective block of adenosine A(2A) receptors prevents ischaemic‐like effects induced by oxygen and glucose deprivation in rat medium spiny neurons

BACKGROUND AND PURPOSE: Ischaemia is known to cause massive neuronal depolarization, termed anoxic depolarization (AD), due to energy failure and loss of membrane ion gradients. The neuromodulator adenosine accumulates extracellularly during ischaemia and activates four metabotropic receptors: A(1),...

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Detalles Bibliográficos
Autores principales: Coppi, Elisabetta, Gibb, Alasdair J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796695/
https://www.ncbi.nlm.nih.gov/pubmed/35817954
http://dx.doi.org/10.1111/bph.15922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796695/
https://www.ncbi.nlm.nih.gov/pubmed/35817954
http://dx.doi.org/10.1111/bph.15922

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