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Selective block of adenosine A(2A) receptors prevents ischaemic‐like effects induced by oxygen and glucose deprivation in rat medium spiny neurons
BACKGROUND AND PURPOSE: Ischaemia is known to cause massive neuronal depolarization, termed anoxic depolarization (AD), due to energy failure and loss of membrane ion gradients. The neuromodulator adenosine accumulates extracellularly during ischaemia and activates four metabotropic receptors: A(1),...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796695/ https://www.ncbi.nlm.nih.gov/pubmed/35817954 http://dx.doi.org/10.1111/bph.15922 |