Nudix hydrolase 15 (NUDT15) loss‐of‐function variants in an Australian inflammatory bowel disease population

BACKGROUND: Thiopurine‐related adverse events such as leukopenia, liver dysfunction and pancreatitis are associated with variants in the NUDT15 gene. Loss‐of‐function (low or no enzyme activity) alleles are more common in Asian and Hispanic populations. The prevalence of these variants in the Austra...

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Detalles Bibliográficos
Autores principales: Afrin, Sadia, Simms, Lisa A., Lord, Anton, Radford‐Smith, Graham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796699/
https://www.ncbi.nlm.nih.gov/pubmed/35289057
http://dx.doi.org/10.1111/imj.15746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796699/
https://www.ncbi.nlm.nih.gov/pubmed/35289057
http://dx.doi.org/10.1111/imj.15746

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