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Nudix hydrolase 15 (NUDT15) loss‐of‐function variants in an Australian inflammatory bowel disease population
BACKGROUND: Thiopurine‐related adverse events such as leukopenia, liver dysfunction and pancreatitis are associated with variants in the NUDT15 gene. Loss‐of‐function (low or no enzyme activity) alleles are more common in Asian and Hispanic populations. The prevalence of these variants in the Austra...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons Australia, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796699/ https://www.ncbi.nlm.nih.gov/pubmed/35289057 http://dx.doi.org/10.1111/imj.15746 |