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The pharmacology of blinatumomab: state of the art on pharmacodynamics, pharmacokinetics, adverse drug reactions and evaluation in clinical trials
WHAT IS KNOWN AND OBJECTIVE: Bispecific drugs (BDs) belong to the family of immunotherapies along with checkpoint inhibitors and CAR‐T cells. In the field of oncology, BDs are designed to simultaneously bind a tumour antigen on the one side and an antigen present on the surface of effector cells on...
Autores principales: | Mocquot, Pauline, Mossazadeh, Yasmine, Lapierre, Léopoldine, Pineau, Fanny, Despas, Fabien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796714/ https://www.ncbi.nlm.nih.gov/pubmed/35906791 http://dx.doi.org/10.1111/jcpt.13741 |
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