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RNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2

Embryonic stem cells (ESCs) are self-renewing and pluripotent. In recent years, factors that control pluripotency, mostly nuclear, have been identified. To identify non-nuclear regulators of ESCs, we screened an endogenously labeled fluorescent fusion-protein library in mouse ESCs. One of the more c...

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Detalles Bibliográficos
Autores principales: Viegas, Juliane O., Azad, Gajendra Kumar, Lv, Yuan, Fishman, Lior, Paltiel, Tal, Pattabiraman, Sundararaghavan, Park, Jung Eun, Kaganovich, Daniel, Sze, Siu Kwan, Rabani, Michal, Esteban, Miguel A., Meshorer, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796812/
https://www.ncbi.nlm.nih.gov/pubmed/36495875
http://dx.doi.org/10.1016/j.devcel.2022.11.014