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Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions

BACKGROUND: Immediate drug hypersensitivity reactions (IDHRs) to clavulanic acid (CLV) have increased in the last decades due to a higher consumption alongside amoxicillin (AX). Due to its chemical instability, diagnostic procedures to evaluate IDHRs to CLV are difficult, and current in vitro assays...

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Detalles Bibliográficos
Autores principales: Fernandez‐Santamaria, Ruben, Bogas, Gador, Montañez, Maria Isabel, Ariza, Adriana, Salas, Maria, Cespedes, Jose Antonio, Labella, Marina, Paris, Juan Luis, Perez‐Sanchez, Natalia, Perez‐Inestrosa, Ezequiel, Vida, Yolanda, Fernandez, Tahia D., Mayorga, Cristobalina, Torres, Maria Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796838/
https://www.ncbi.nlm.nih.gov/pubmed/35611454
http://dx.doi.org/10.1111/all.15383