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CUSUMIN: A cumulative sum interval design for cancer phase I dose finding studies

Recently, model‐assisted designs, including the Bayesian optimal interval (BOIN) design with optimal thresholds to determine the dose for the next cohort, have been proposed for cancer phase I studies. Model‐assisted designs are useful because of their good performance as model‐based designs in addi...

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Detalles Bibliográficos
Autores principales: Hatayama, Tomoyoshi, Yasui, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796866/
https://www.ncbi.nlm.nih.gov/pubmed/35833753
http://dx.doi.org/10.1002/pst.2247