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Structural basis for the inhibition of human angiotensin‐1 converting enzyme by fosinoprilat
Human angiotensin I‐converting enzyme (ACE) has two isoforms, somatic ACE (sACE) and testis ACE (tACE). The functions of sACE are widespread, with its involvement in blood pressure regulation most extensively studied. sACE is composed of an N‐domain (nACE) and a C‐domain (cACE), both catalytically a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796954/ https://www.ncbi.nlm.nih.gov/pubmed/35653492 http://dx.doi.org/10.1111/febs.16543 |