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Endogenous tagging of Unc-13 reveals nanoscale reorganization at active zones during presynaptic homeostatic potentiation

INTRODUCTION: Neurotransmitter release at presynaptic active zones (AZs) requires concerted protein interactions within a dense 3D nano-hemisphere. Among the complex protein meshwork the (M)unc-13 family member Unc-13 of Drosophila melanogaster is essential for docking of synaptic vesicles and trans...

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Detalles Bibliográficos
Autores principales: Dannhäuser, Sven, Mrestani, Achmed, Gundelach, Florian, Pauli, Martin, Komma, Fabian, Kollmannsberger, Philip, Sauer, Markus, Heckmann, Manfred, Paul, Mila M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797049/
https://www.ncbi.nlm.nih.gov/pubmed/36589286
http://dx.doi.org/10.3389/fncel.2022.1074304