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Two distinct lipid transporters together regulate invasive filamentous growth in the human fungal pathogen Candida albicans

Flippases transport lipids across the membrane bilayer to generate and maintain asymmetry. The human fungal pathogen Candida albicans has 5 flippases, including Drs2, which is critical for filamentous growth and phosphatidylserine (PS) distribution. Furthermore, a drs2 deletion mutant is hypersensit...

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Detalles Bibliográficos
Autores principales: Basante-Bedoya, Miguel A., Bogliolo, Stéphanie, Garcia-Rodas, Rocio, Zaragoza, Oscar, Arkowitz, Robert A., Bassilana, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797089/
https://www.ncbi.nlm.nih.gov/pubmed/36516161
http://dx.doi.org/10.1371/journal.pgen.1010549