Sequence-sensitive elastic network captures dynamical features necessary for miR-125a maturation

The Elastic Network Contact Model (ENCoM) is a coarse-grained normal mode analysis (NMA) model unique in its all-atom sensitivity to the sequence of the studied macromolecule and thus to the effect of mutations. We adapted ENCoM to simulate the dynamics of ribonucleic acid (RNA) molecules, benchmark...

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Detalles Bibliográficos
Autores principales: Mailhot, Olivier, Frappier, Vincent, Major, François, Najmanovich, Rafael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797095/
https://www.ncbi.nlm.nih.gov/pubmed/36516216
http://dx.doi.org/10.1371/journal.pcbi.1010777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797095/
https://www.ncbi.nlm.nih.gov/pubmed/36516216
http://dx.doi.org/10.1371/journal.pcbi.1010777

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