Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells

BACKGROUND: Airway fibrosis is one of the pathological characteristics of severe asthma. Transforming growth factor (TGF)-β has been known to promote epithelial-mesenchymal transition formation and to play a role in the progression of tissue fibrosis. Cellular communication network factor 2 (CCN2) a...

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Detalles Bibliográficos
Autores principales: Cheng, Wun-Hao, Kao, Shih-Ya, Chen, Chia-Ling, Yuliani, Fara Silvia, Lin, Lee-Yuan, Lin, Chien-Huang, Chen, Bing-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797108/
https://www.ncbi.nlm.nih.gov/pubmed/36578010
http://dx.doi.org/10.1186/s12931-022-02285-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797108/
https://www.ncbi.nlm.nih.gov/pubmed/36578010
http://dx.doi.org/10.1186/s12931-022-02285-2

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