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Macrophages and microglia in glioblastoma: heterogeneity, plasticity, and therapy

Glioblastoma (GBM) is the most aggressive tumor in the central nervous system and contains a highly immunosuppressive tumor microenvironment (TME). Tumor-associated macrophages and microglia (TAMs) are a dominant population of immune cells in the GBM TME that contribute to most GBM hallmarks, includ...

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Detalles Bibliográficos
Autores principales: Khan, Fatima, Pang, Lizhi, Dunterman, Madeline, Lesniak, Maciej S., Heimberger, Amy B., Chen, Peiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797335/
https://www.ncbi.nlm.nih.gov/pubmed/36594466
http://dx.doi.org/10.1172/JCI163446