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IL-10-producing Th1 cells possess a distinct molecular signature in malaria
Control of intracellular parasites responsible for malaria requires host IFN-γ(+)T-bet(+)CD4(+) T cells (Th1 cells) with IL-10 produced by Th1 cells to mitigate the pathology induced by this inflammatory response. However, these IL-10–producing Th1 (induced type I regulatory [Tr1]) cells can also pr...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797345/ https://www.ncbi.nlm.nih.gov/pubmed/36594463 http://dx.doi.org/10.1172/JCI153733 |