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Cyclophilin A binds to AKT1 and facilitates the tumorigenicity of Epstein-Barr virus by mediating the activation of AKT/mTOR/NF-κB positive feedback loop

The AKT/mTOR and NF-κB signalings are crucial pathways activated in cancers including nasopharyngeal carcinoma (NPC), which is prevalent in southern China and closely related to Epstein-Barr virus (EBV) infection. How these master pathways are persistently activated in EBV-associated NPC remains to...

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Detalles Bibliográficos
Autores principales: Xin, Shuyu, Liu, Lingzhi, Li, Yanling, Yang, Jing, Zuo, Lielian, Cao, Pengfei, Yan, Qijia, Li, Shen, Yang, Li, Cui, Taimei, Lu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797372/
https://www.ncbi.nlm.nih.gov/pubmed/36075565
http://dx.doi.org/10.1016/j.virs.2022.09.001