Antibacterial and anti-biofilm activity of diarylureas against Enterococcus faecium by suppressing the gene expression of peptidoglycan hydrolases and adherence

Enterococcus faecium (E. faecium) is a clinical multidrug-resistant pathogen causing life-threatening infection, which makes it important to discover antibacterial agents with novel scaffolds and unique mechanism. In this study, the diarylurea scaffold was found to have potent antibacterial effect o...

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Detalles Bibliográficos
Autores principales: Xie, Yunfeng, Wang, Lei, Yang, Yang, Zha, Liang, Zhang, Jiazhen, Rong, Kuanrong, Tang, Wenjian, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797508/
https://www.ncbi.nlm.nih.gov/pubmed/36590419
http://dx.doi.org/10.3389/fmicb.2022.1071255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797508/
https://www.ncbi.nlm.nih.gov/pubmed/36590419
http://dx.doi.org/10.3389/fmicb.2022.1071255

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