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Antibacterial and anti-biofilm activity of diarylureas against Enterococcus faecium by suppressing the gene expression of peptidoglycan hydrolases and adherence
Enterococcus faecium (E. faecium) is a clinical multidrug-resistant pathogen causing life-threatening infection, which makes it important to discover antibacterial agents with novel scaffolds and unique mechanism. In this study, the diarylurea scaffold was found to have potent antibacterial effect o...
Autores principales: | Xie, Yunfeng, Wang, Lei, Yang, Yang, Zha, Liang, Zhang, Jiazhen, Rong, Kuanrong, Tang, Wenjian, Zhang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797508/ https://www.ncbi.nlm.nih.gov/pubmed/36590419 http://dx.doi.org/10.3389/fmicb.2022.1071255 |
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