Discovery of imidazole-based GSK-3β inhibitors for transdifferentiation of human mesenchymal stem cells to neurons: A potential single-molecule neurotherapeutic foresight

The transdifferentiation of human mesenchymal stem cells (hMSC) to functional neurons is crucial for the development of future neuro-regenerative therapeutics. Currently, transdifferentiation of hMSCs to neurons requires a “chemical cocktail” along with neural growth factors. The role of the individ...

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Detalles Bibliográficos
Autores principales: Gupta, Varsha, Mahata, Tanushree, Roy, Rajsekhar, Gharai, Prabir Kumar, Jana, Aniket, Garg, Shubham, Ghosh, Surajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797524/
https://www.ncbi.nlm.nih.gov/pubmed/36590911
http://dx.doi.org/10.3389/fnmol.2022.1002419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797524/
https://www.ncbi.nlm.nih.gov/pubmed/36590911
http://dx.doi.org/10.3389/fnmol.2022.1002419

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