Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy

Cardiomyopathies have unresolved genotype–phenotype relationships and lack disease-specific treatments. Here we provide a framework to identify genotype-specific pathomechanisms and therapeutic targets to accelerate the development of precision medicine. We use human cardiac electromechanical in-sil...

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Detalles Bibliográficos
Autores principales: Margara, Francesca, Psaras, Yiangos, Wang, Zhinuo Jenny, Schmid, Manuel, Doste, Ruben, Garfinkel, Amanda C., Repetti, Giuliana G., Seidman, Jonathan G., Seidman, Christine E., Rodriguez, Blanca, Toepfer, Christopher N., Bueno-Orovio, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797561/
https://www.ncbi.nlm.nih.gov/pubmed/36577774
http://dx.doi.org/10.1038/s41598-022-26889-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797561/
https://www.ncbi.nlm.nih.gov/pubmed/36577774
http://dx.doi.org/10.1038/s41598-022-26889-2

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