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LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence

Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF), which controls fundamental biological processes such as cell growth, migration, and differentiation. MRTF and SRF transcriptional activity play an important role in hepatocellular carcinoma (HCC)...

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Detalles Bibliográficos
Autores principales: Konopa, Andreas, Meier, Melanie A., Franz, Miriam J., Bernardinelli, Emanuele, Voegele, Anna-Lena, Atreya, Raja, Ribback, Silvia, Roessler, Stephanie, Aigner, Achim, Singer, Kerstin, Singer, Stephan, Sarikas, Antonio, Muehlich, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797565/
https://www.ncbi.nlm.nih.gov/pubmed/36577757
http://dx.doi.org/10.1038/s41389-022-00445-z