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LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence
Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF), which controls fundamental biological processes such as cell growth, migration, and differentiation. MRTF and SRF transcriptional activity play an important role in hepatocellular carcinoma (HCC)...
Autores principales: | Konopa, Andreas, Meier, Melanie A., Franz, Miriam J., Bernardinelli, Emanuele, Voegele, Anna-Lena, Atreya, Raja, Ribback, Silvia, Roessler, Stephanie, Aigner, Achim, Singer, Kerstin, Singer, Stephan, Sarikas, Antonio, Muehlich, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797565/ https://www.ncbi.nlm.nih.gov/pubmed/36577757 http://dx.doi.org/10.1038/s41389-022-00445-z |
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