Cargando…

LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence

Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF), which controls fundamental biological processes such as cell growth, migration, and differentiation. MRTF and SRF transcriptional activity play an important role in hepatocellular carcinoma (HCC)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Konopa, Andreas, Meier, Melanie A., Franz, Miriam J., Bernardinelli, Emanuele, Voegele, Anna-Lena, Atreya, Raja, Ribback, Silvia, Roessler, Stephanie, Aigner, Achim, Singer, Kerstin, Singer, Stephan, Sarikas, Antonio, Muehlich, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797565/ https://www.ncbi.nlm.nih.gov/pubmed/36577757 http://dx.doi.org/10.1038/s41389-022-00445-z

Ejemplares similares

G Protein-Coupled Receptors Directly Bind Filamin A with High Affinity and Promote Filamin Phosphorylation
por: Tirupula, Kalyan C., et al.
Publicado: (2015)

Localization of filamin in smooth muscle
Publicado: (1986)

Structural basis of filamin A functions
por: Nakamura, Fumihiko, et al.
Publicado: (2007)

Filamin A modulates platelet function
por: Lopez, Jose J., et al.
Publicado: (2018)

Filamin A Regulates Cardiovascular Remodeling
por: Bandaru, Sashidar, et al.
Publicado: (2021)

Filamin A-Hinge Region 1-EGFP: A Novel Tool for Tracking the Cellular Functions of Filamin A in Real-Time
por: Planagumà, Jesús, et al.
Publicado: (2012)

Indications for a Novel Muscular Dystrophy Pathway: γ-Filamin, the Muscle-Specific Filamin Isoform, Interacts with Myotilin
por: van der Ven, Peter F.M., et al.
Publicado: (2000)

Molecular Basis of Filamin A-FilGAP Interaction and Its Impairment in Congenital Disorders Associated with Filamin A Mutations
por: Nakamura, Fumihiko, et al.
Publicado: (2009)

Filamin A increases aggressiveness of human neuroblastoma
por: Bandaru, Sashidar, et al.
Publicado: (2022)

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence
por: Hampl, Veronika, et al.
Publicado: (2013)

Structural mechanism of integrin inactivation by filamin
por: Liu, Jianmin, et al.
Publicado: (2015)

Inhibition of Filamin-A Reduces Cancer Metastatic Potential
por: Jiang, Xi, et al.
Publicado: (2012)

Biological roles of filamin a in prostate cancer cells
por: Li, Xue-Chao, et al.
Publicado: (2019)

Switching of filamin polypeptides during myogenesis in vitro
Publicado: (1983)

Evidence for the mechanosensor function of filamin in tissue development
por: Huelsmann, Sven, et al.
Publicado: (2016)

Filamin C is Essential for mammalian myocardial integrity
por: Wu, Tongbin, et al.
Publicado: (2023)

Inhibition of LPA-LPAR1 and VEGF-VEGFR2 Signaling in IPF Treatment
por: Luo, Ya-Li, et al.
Publicado: (2023)

Significance of filamin A in mTORC2 function in glioblastoma
por: Chantaravisoot, Naphat, et al.
Publicado: (2015)

Identification of Filamin-A and -B as potential biomarkers for prostate cancer
por: Narain, Niven R, et al.
Publicado: (2016)

Nogo-A regulates myogenesis via interacting with Filamin-C
por: Park, SunYoung, et al.
Publicado: (2021)

Molecular Tuning of Filamin A Activities in the Context of Adhesion and Migration
por: Lamsoul, Isabelle, et al.
Publicado: (2020)

Clinicopathological significance of immunohistochemical expression of Filamin A in breast cancer
por: Joshua, Lokavarapu Manoj, et al.
Publicado: (2020)

Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection
por: Chen, Yue, et al.
Publicado: (2021)

Clinical management of a pregnant woman with Filamin C cardiomyopathy
por: Bariani, Riccardo, et al.
Publicado: (2022)

Molecular docking analysis of protein filamin-A with thioazo compounds
por: Satish, Sudarshan, et al.
Publicado: (2023)

Role of filamin A in the pathogenesis of neuroendocrine tumors and adrenal cancer
por: Treppiedi, Donatella, et al.
Publicado: (2022)

Structural Interaction and Functional Regulation of Polycystin-2 by Filamin
por: Wang, Qian, et al.
Publicado: (2012)

Filamins Regulate Cell Spreading and Initiation of Cell Migration
por: Baldassarre, Massimiliano, et al.
Publicado: (2009)

Structure and Function of Filamin C in the Muscle Z-Disc
por: Mao, Zhenfeng, et al.
Publicado: (2020)

Sinus of Valsalva Aneurysm: A Potential Case of Filamin A Mutation
por: Win, Soe, et al.
Publicado: (2023)

Filamin A Binds to CCR2B and Regulates Its Internalization
por: Minsaas, Laura, et al.
Publicado: (2010)

Combined cardiological and neurological abnormalities due to filamin A gene mutation
por: de Wit, Marie Claire Y., et al.
Publicado: (2010)

Prognostic Values of Filamin-A Status for Topoisomerase II Poison Chemotherapy
por: Yue, Jingyin, et al.
Publicado: (2012)

Ureaplasma parvum infection alters filamin a dynamics in host cells
por: Allam, Ayman B, et al.
Publicado: (2011)

Complex roles of filamin-A mediated cytoskeleton network in cancer progression
por: Yue, Jingyin, et al.
Publicado: (2013)

Differential expression of filamin A and its clinical significance in breast cancer
por: TIAN, HUI-MIN, et al.
Publicado: (2013)

Filamin-A Increases the Stability and Plasma Membrane Expression of Polycystin-2
por: Wang, Qian, et al.
Publicado: (2015)

Filamin A phosphorylation by Akt promotes cell migration in response to arsenic
por: Li, Lingzhi, et al.
Publicado: (2015)

Asparagine Synthetase and Filamin A Have Different Roles in Ovarian Cancer
por: Zeng, Liang, et al.
Publicado: (2019)

Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells
por: Levert, Stéphanie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8orrtp6i26rei40bh362r3ivd9