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Deep learning-based multi-drug synergy prediction model for individually tailored anti-cancer therapies

While synergistic drug combinations are more effective at fighting tumors with complex pathophysiology, preference compensating mechanisms, and drug resistance, the identification of novel synergistic drug combinations, especially complex higher-order combinations, remains challenging due to the siz...

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Detalles Bibliográficos
Autores principales: She, Shengnan, Chen, Hengwei, Ji, Wei, Sun, Mengqiu, Cheng, Jiaxi, Rui, Mengjie, Feng, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797718/
https://www.ncbi.nlm.nih.gov/pubmed/36588694
http://dx.doi.org/10.3389/fphar.2022.1032875