Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein

The complement system is one of the first defense lines protecting from invading pathogens. However, it may turn offensive to the body’s own cells and tissues when deregulated by the presence of rare genetic variants that impair physiological regulation and/or provoke abnormal activity of key enzyma...

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Detalles Bibliográficos
Autores principales: Kuźniewska, Alicja, Thiel, Marcel, Kowalska, Daria, Felberg-Miętka, Anna, Szynkowski, Patryk, Ołdziej, Stanisław, Arjona, Emilia, Jongerius, Ilse, Rodriguez de Córdoba, Santiago, Okrój, Marcin, Urban, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797810/
https://www.ncbi.nlm.nih.gov/pubmed/36591303
http://dx.doi.org/10.3389/fimmu.2022.1061696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797810/
https://www.ncbi.nlm.nih.gov/pubmed/36591303
http://dx.doi.org/10.3389/fimmu.2022.1061696

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