BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells

P2X7 receptor (P2RX7) is expressed strongly by most human cancers, including neuroblastoma, where high levels of P2RX7 are correlated with a poor prognosis for patients. Tonic activation of P2X7 receptor favors cell metabolism and angiogenesis, thereby promoting cancer cell proliferation, immunosupp...

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Detalles Bibliográficos
Autores principales: Benito-León, María, Gil-Redondo, Juan Carlos, Perez-Sen, Raquel, Delicado, Esmerilda G., Ortega, Felipe, Gomez-Villafuertes, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797830/
https://www.ncbi.nlm.nih.gov/pubmed/36589747
http://dx.doi.org/10.3389/fcell.2022.1049566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797830/
https://www.ncbi.nlm.nih.gov/pubmed/36589747
http://dx.doi.org/10.3389/fcell.2022.1049566

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