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β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility

Sperm chemotaxis is required for guiding sperm toward the egg. However, the molecular identity of physiological chemoattractant and its involvement in infertility remain elusive. Here, we identify DEFB19/119 (mouse/human orthologs) as a physiological sperm chemoattractant. The epithelia of the femal...

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Detalles Bibliográficos
Autores principales: Li, Xiaofeng, Yuan, Chun, Shi, Jianwu, Kang, Hang, Chen, Yufei, Duan, Yonggang, Jin, Jing, Cheung, Lai Ping, Li, Tin Chiu, Liu, Ying, Cui, Yugui, Ruan, Ye Chun, Jiang, Xiaohua, Cai, Zhiming, Chan, Hsiao Chang, Ji, Ling, Zeng, Xuhui, Liu, Jiaying, Chen, Hao, Fok, Kin Lam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797948/
https://www.ncbi.nlm.nih.gov/pubmed/36513070
http://dx.doi.org/10.1016/j.xcrm.2022.100825