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A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations

Limited sensitivity and specificity of current diagnostics lead to the erroneous prescription of antibiotics. Host-response-based diagnostics could address these challenges. However, using 4,200 samples across 69 blood transcriptome datasets from 20 countries from patients with bacterial or viral in...

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Detalles Bibliográficos
Autores principales: Rao, Aditya M., Popper, Stephen J., Gupta, Sanjana, Davong, Viengmon, Vaidya, Krista, Chanthongthip, Anisone, Dittrich, Sabine, Robinson, Matthew T., Vongsouvath, Manivanh, Mayxay, Mayfong, Nawtaisong, Pruksa, Karmacharya, Biraj, Thair, Simone A., Bogoch, Isaac, Sweeney, Timothy E., Newton, Paul N., Andrews, Jason R., Relman, David A., Khatri, Purvesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797950/
https://www.ncbi.nlm.nih.gov/pubmed/36543117
http://dx.doi.org/10.1016/j.xcrm.2022.100842