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TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Limitation of excessive inflammation due to selective degradation of pro-inflammatory proteins is one of the cytoprotective functions attributed to autophagy. In the current study, we highlight that selective autophagy also plays a vital role in promoting the establishment of a robust inflammatory r...

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Detalles Bibliográficos
Autores principales: Zhou, Jianwen, Rasmussen, Nikoline Lander, Olsvik, Hallvard Lauritz, Akimov, Vyacheslav, Hu, Zehan, Evjen, Gry, Kaeser-Pebernard, Stéphanie, Sankar, Devanarayanan Siva, Roubaty, Carole, Verlhac, Pauline, van de Beek, Nicole, Reggiori, Fulvio, Abudu, Yakubu Princely, Blagoev, Blagoy, Lamark, Trond, Johansen, Terje, Dengjel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797988/
https://www.ncbi.nlm.nih.gov/pubmed/36574265
http://dx.doi.org/10.1083/jcb.202108144