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Cysteine-specific (89)Zr-labeled anti-CD25 IgG allows immuno-PET imaging of interleukin-2 receptor-α on T cell lymphomas

INTRODUCTION: Positron emission tomography (PET) using radiolabeled Abs as imaging tracer is called immuno-PET. Immuno-PET can verify therapeutic Ab delivery and can noninvasively quantify global levels of target expression in tumors of living subjects. The interleukin-2 receptor α chain (IL-2Rα; CD...

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Detalles Bibliográficos
Autores principales: Lee, Jin Hee, Jung, Kyung-Ho, Kim, Mina, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9797992/
https://www.ncbi.nlm.nih.gov/pubmed/36591250
http://dx.doi.org/10.3389/fimmu.2022.1017132