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MicroRNA-dependent suppression of biological pacemaker activity induced by TBX18

Chemically modified mRNA (CMmRNA) with selectively altered nucleotides are used to deliver transgenes, but translation efficiency is variable. We have transfected CMmRNA encoding human T-box transcription factor 18 (CMmTBX18) into heart cells or the left ventricle of rats with atrioventricular block...

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Detalles Bibliográficos
Autores principales: Sanchez, Lizbeth, Mesquita, Thassio, Zhang, Rui, Liao, Ke, Rogers, Russell, Lin, Yen-Nien, Miguel-dos-Santos, Rodrigo, Akhmerov, Akbarshakh, Li, Liang, Nawaz, Asma, Holm, Kevin, Marbán, Eduardo, Cingolani, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798022/
https://www.ncbi.nlm.nih.gov/pubmed/36543116
http://dx.doi.org/10.1016/j.xcrm.2022.100871