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Exome-wide association analysis of CT imaging-derived hepatic fat in a medical biobank

Nonalcoholic fatty liver disease is common and highly heritable. Genetic studies of hepatic fat have not sufficiently addressed non-European and rare variants. In a medical biobank, we quantitate hepatic fat from clinical computed tomography (CT) scans via deep learning in 10,283 participants with w...

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Detalles Bibliográficos
Autores principales: Park, Joseph, MacLean, Matthew T., Lucas, Anastasia M., Torigian, Drew A., Schneider, Carolin V., Cherlin, Tess, Xiao, Brenda, Miller, Jason E., Bradford, Yuki, Judy, Renae L., Verma, Anurag, Damrauer, Scott M., Ritchie, Marylyn D., Witschey, Walter R., Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798024/
https://www.ncbi.nlm.nih.gov/pubmed/36513072
http://dx.doi.org/10.1016/j.xcrm.2022.100855