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Deep learning identifies morphological patterns of homologous recombination deficiency in luminal breast cancers from whole slide images
Homologous recombination DNA-repair deficiency (HRD) is becoming a well-recognized marker of platinum salt and polyADP-ribose polymerase inhibitor chemotherapies in ovarian and breast cancers. While large-scale screening for HRD using genomic markers is logistically and economically challenging, sta...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798078/ https://www.ncbi.nlm.nih.gov/pubmed/36516847 http://dx.doi.org/10.1016/j.xcrm.2022.100872 |