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Deep learning identifies morphological patterns of homologous recombination deficiency in luminal breast cancers from whole slide images

Homologous recombination DNA-repair deficiency (HRD) is becoming a well-recognized marker of platinum salt and polyADP-ribose polymerase inhibitor chemotherapies in ovarian and breast cancers. While large-scale screening for HRD using genomic markers is logistically and economically challenging, sta...

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Detalles Bibliográficos
Autores principales: Lazard, Tristan, Bataillon, Guillaume, Naylor, Peter, Popova, Tatiana, Bidard, François-Clément, Stoppa-Lyonnet, Dominique, Stern, Marc-Henri, Decencière, Etienne, Walter, Thomas, Vincent-Salomon, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798078/
https://www.ncbi.nlm.nih.gov/pubmed/36516847
http://dx.doi.org/10.1016/j.xcrm.2022.100872