Aryl acrylonitriles synthesis enabled by palladium-catalyzed α-alkenylation of arylacetonitriles with vinyl halides/triflates

Aryl acrylonitriles are an important subclass of acrylonitriles in the medicinal chemistry and pharmaceutical industry. Herein, an efficient synthesis of aryl acrylonitrile derivatives using a Palladium/NIXANTPHOS-based catalyst system was developed. This approach furnishes a variety of substituted...

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Detalles Bibliográficos
Autores principales: Jiang, Yonggang, Wang, Bijun, Liu, Dongxiang, Xia, Dazhen, Liu, Zhengfen, Li, Liang, Deng, Guogang, Yang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798101/
https://www.ncbi.nlm.nih.gov/pubmed/36590282
http://dx.doi.org/10.3389/fchem.2022.1091566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798101/
https://www.ncbi.nlm.nih.gov/pubmed/36590282
http://dx.doi.org/10.3389/fchem.2022.1091566

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