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Aryl acrylonitriles synthesis enabled by palladium-catalyzed α-alkenylation of arylacetonitriles with vinyl halides/triflates
Aryl acrylonitriles are an important subclass of acrylonitriles in the medicinal chemistry and pharmaceutical industry. Herein, an efficient synthesis of aryl acrylonitrile derivatives using a Palladium/NIXANTPHOS-based catalyst system was developed. This approach furnishes a variety of substituted...
Autores principales: | Jiang, Yonggang, Wang, Bijun, Liu, Dongxiang, Xia, Dazhen, Liu, Zhengfen, Li, Liang, Deng, Guogang, Yang, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798101/ https://www.ncbi.nlm.nih.gov/pubmed/36590282 http://dx.doi.org/10.3389/fchem.2022.1091566 |
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