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Phosphoproteomics data-driven signalling network inference: Does it work?

The advent of global phosphoproteome profiling has led to wide phosphosite coverage and therefore the opportunity to predict kinase-substrate associations from these datasets. However, the regulatory kinase is unknown for most substrates, due to biased and incomplete database annotations. In this st...

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Detalles Bibliográficos
Autores principales: Sriraja, Lourdes O., Werhli, Adriano, Petsalaki, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798138/
https://www.ncbi.nlm.nih.gov/pubmed/36618990
http://dx.doi.org/10.1016/j.csbj.2022.12.010