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Artificial intelligence-driven meta-analysis of brain gene expression identifies novel gene candidates and a role for mitochondria in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia. There is no treatment and AD models have focused on a small subset of genes identified in familial AD. Microarray studies have identified thousands of dysregulated genes in the brains of patients with AD yet identifying the best gene cand...

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Detalles Bibliográficos
Autores principales: Finney, Caitlin A., Delerue, Fabien, Gold, Wendy A., Brown, David A., Shvetcov, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798142/
https://www.ncbi.nlm.nih.gov/pubmed/36618979
http://dx.doi.org/10.1016/j.csbj.2022.12.018