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Interference of ALOX5 alleviates inflammation and fibrosis in high glucose‑induced renal mesangial cells

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), seriously threatening the health of individuals. The 5-lipoxygenase (ALOX5) gene has been reported to be associated with diabetes, but whether it is involved in DN remains unclear. The present study aimed to explore th...

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Detalles Bibliográficos
Autores principales: Chen, Xiaotao, Xie, Hongwu, Liu, Yun, Ou, Qiujuan, Deng, Shuaijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798157/
https://www.ncbi.nlm.nih.gov/pubmed/36605525
http://dx.doi.org/10.3892/etm.2022.11733