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Experimental and computational analysis of the ancestry of an evolutionary young enzyme from histidine biosynthesis
The conservation of fold and chemistry of the enzymes associated with histidine biosynthesis suggests that this pathway evolved prior to the diversification of Bacteria, Archaea, and Eukaryotes. The only exception is the histidinol phosphate phosphatase (HolPase). So far, non‐homologous HolPases tha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798254/ https://www.ncbi.nlm.nih.gov/pubmed/36502290 http://dx.doi.org/10.1002/pro.4536 |