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In silico mechanisms of arsenic trioxide-induced cardiotoxicity

It has been found that arsenic trioxide (ATO) is effective in treating acute promyelocytic leukemia (APL). However, long QT syndrome was reported in patients receiving therapy using ATO, which even led to sudden cardiac death. The underlying mechanisms of ATO-induced cardiotoxicity have been investi...

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Detalles Bibliográficos
Autores principales: Li, Yacong, Wan, Runlan, Liu, Jun, Liu, Weichao, Ma, Lei, Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798418/
https://www.ncbi.nlm.nih.gov/pubmed/36589437
http://dx.doi.org/10.3389/fphys.2022.1004605