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Transporter and metabolizer gene polymorphisms affect fluoroquinolone pharmacokinetic parameters

Tuberculosis (TB) is an infectious disease that occurs globally. Treatment of TB has been hindered by problems with multidrug-resistant strains (MDR-TB). Fluoroquinolones are one of the main drugs used for the treatment of MDR-TB. The success of therapy can be influenced by genetic factors and their...

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Detalles Bibliográficos
Autores principales: Annisa, Nurul, Barliana, Melisa I., Santoso, Prayudi, Ruslami, Rovina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798452/
https://www.ncbi.nlm.nih.gov/pubmed/36588725
http://dx.doi.org/10.3389/fphar.2022.1063413