Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis

Recent work showed that the dominant post-menopausal estrogen, estrone, cooperates with nuclear factor κB (NF-κB) to stimulate inflammation, while pre-menopausal 17β-estradiol opposes NF-κB. Here, we show that post-menopausal estrone, but not 17β-estradiol, activates epithelial-to-mesenchymal transi...

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Detalles Bibliográficos
Autores principales: Qureshi, Rehana, Picon-Ruiz, Manuel, Sho, Maiko, Van Booven, Derek, Nunes de Paiva, Vanessa, Diaz-Ruano, Anna B., Ince, Tan A., Slingerland, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798480/
https://www.ncbi.nlm.nih.gov/pubmed/36384125
http://dx.doi.org/10.1016/j.celrep.2022.111672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798480/
https://www.ncbi.nlm.nih.gov/pubmed/36384125
http://dx.doi.org/10.1016/j.celrep.2022.111672

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