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TSG-6 inhibits IL-1β-induced inflammatory responses and extracellular matrix degradation in nucleus pulposus cells by activating the PI3K/Akt signaling pathway

PURPOSE: Tumor necrosis factor (TNF)-stimulated gene-6 (TSG-6), a secreted protein associated with inflammation, is believed to possess momentous and multiple anti-inflammatory and tissue-protective properties. However, the role and potential mechanism of TSG-6 in cervical disk degeneration (CDD) ar...

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Detalles Bibliográficos
Autores principales: Wu, Bing, Guo, Xiaojin, Yan, Xiujie, Tian, Zikai, Jiang, Wei, He, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798563/
https://www.ncbi.nlm.nih.gov/pubmed/36578051
http://dx.doi.org/10.1186/s13018-022-03468-9