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TSG-6 inhibits IL-1β-induced inflammatory responses and extracellular matrix degradation in nucleus pulposus cells by activating the PI3K/Akt signaling pathway
PURPOSE: Tumor necrosis factor (TNF)-stimulated gene-6 (TSG-6), a secreted protein associated with inflammation, is believed to possess momentous and multiple anti-inflammatory and tissue-protective properties. However, the role and potential mechanism of TSG-6 in cervical disk degeneration (CDD) ar...
Autores principales: | Wu, Bing, Guo, Xiaojin, Yan, Xiujie, Tian, Zikai, Jiang, Wei, He, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798563/ https://www.ncbi.nlm.nih.gov/pubmed/36578051 http://dx.doi.org/10.1186/s13018-022-03468-9 |
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