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OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

BACKGROUND: Randall’s plaques (RP) are identified as anchored sites for kidney calcium oxalate stones, but the mechanism remains unclear. Given the importance of osteogenic-like cells in RP formation and OCT4 in reprogramming differentiated cells to osteoblasts, the current study explored the potent...

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Detalles Bibliográficos
Autores principales: Zhu, Zewu, Huang, Fang, Jiang, Yingcheng, Ruan, Shuhao, Liu, Minghui, Zhang, Youjie, Li, Yongchao, Chen, Jinbo, Cui, Yu, Chen, Zhiyong, Chen, Hequn, Zeng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798568/
https://www.ncbi.nlm.nih.gov/pubmed/36581839
http://dx.doi.org/10.1186/s10020-022-00576-4