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Acidic and hypoxic tumor microenvironment regulation by CaO(2)-loaded polydopamine nanoparticles

Hypoxia and high accumulation of lactic acid in the tumor microenvironment provide fertile soil for tumor development, maintenance and metastasis. Herein, we developed a calcium peroxide (CaO(2))-loaded nanostructure that can play a role of “one stone kill two birds”, i.e., acidic and hypoxic tumor...

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Detalles Bibliográficos
Autores principales: Ruan, Shuangrong, Yin, Weimin, Chang, Jiao, Yang, Yan, Sun, Jiuyuan, Ma, Xiaoyi, Liu, Ying, Zang, Jie, Liu, Yiqiong, Li, Yongyong, Ren, Tianbin, Dong, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798656/
https://www.ncbi.nlm.nih.gov/pubmed/36577992
http://dx.doi.org/10.1186/s12951-022-01752-8