Graph regularized non-negative matrix factorization with prior knowledge consistency constraint for drug–target interactions prediction

BACKGROUND: Identifying drug–target interactions (DTIs) plays a key role in drug development. Traditional wet experiments to identify DTIs are expensive and time consuming. Effective computational methods to predict DTIs are useful to narrow the searching scope of potential drugs and speed up the pr...

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Detalles Bibliográficos
Autores principales: Zhang, Junjun, Xie, Minzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798666/
https://www.ncbi.nlm.nih.gov/pubmed/36581822
http://dx.doi.org/10.1186/s12859-022-05119-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798666/
https://www.ncbi.nlm.nih.gov/pubmed/36581822
http://dx.doi.org/10.1186/s12859-022-05119-6

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