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Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells

BACKGROUND: Parental imprinting is an epigenetic mechanism that leads to monoallelic expression of a subset of genes depending on their parental origin. Imprinting disorders (IDs), caused by disturbances of imprinted genes, are a set of rare congenital diseases that mainly affect growth, metabolism...

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Detalles Bibliográficos
Autores principales: Pham, A., Selenou, C., Giabicani, E., Fontaine, V., Marteau, S., Brioude, F., David, L., Mitanchez, D., Sobrier, M. L., Netchine, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798676/
https://www.ncbi.nlm.nih.gov/pubmed/36578048
http://dx.doi.org/10.1186/s13148-022-01410-8