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An Extended DNA Binding Domain of the Estrogen Receptor Alpha Directly Interacts with RNAs in Vitro

[Image: see text] Estrogen receptor alpha (ERα) is a ligand-responsive transcription factor critical for sex determination and development. Recent reports challenge the canonical view of ERα function by suggesting an activity beyond binding dsDNA at estrogen-responsive promotor elements: association...

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Detalles Bibliográficos
Autores principales: Steiner, Halley R., Lammer, Nickolaus C., Batey, Robert T., Wuttke, Deborah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798703/
https://www.ncbi.nlm.nih.gov/pubmed/36239332
http://dx.doi.org/10.1021/acs.biochem.2c00536